Human IL6ST / CD130 / gp130 Protein (Recombinant His-Fc) (Met1-Ile618)

LifeSpan BioSciences

Human IL6ST / CD130 / gp130 Protein (Recombinant His-Fc) (Met1-Ile618)

23

Research Use Only

>95%

IL6ST

interleukin 6 cytokine family signal transducer

CD130, CDW130, GP130, HIES4, HIES4A, HIES4B, IL-6RB, IMD94, STWS2, sGP130, interleukin-6 receptor subunit beta, CD130 antigen, IL-6 receptor subunit beta, IL-6R subunit beta, gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form, gp130, oncostatin M receptor, interleukin receptor beta chain, interleukin-6 signal transducer, membrane glycoprotein 130, membrane glycoprotein gp130, oncostatin-M receptor subunit alpha

The recombinant human IL6ST/Fc is a disulfide-linked homodimer after removal of the signal peptide. The reduced monomer consists of 844 amino acids and has a predicted molecular mass of 96 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh IL6ST/Fc monomer is approximately 125-140 kDa due to glycosylation. A DNA sequence encoding the extracellular domain (Met 1-Ile 618) of human IL6ST (NP_002175.2) precursor was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.

-80°C

41116100

Human