WB analysis of GTX00118-pro Human IL7 protein (active).
Human IL7 protein (active)
GTX00118-PRO
ApplicationsFunctional Assay
Product group Proteins / Signaling Molecules
Protein IDP13232
Overview
- SupplierGeneTex
- Product NameHuman IL7 protein (active)
- Delivery Days Customer9
- ApplicationsFunctional Assay
- CertificationResearch Use Only
- ConjugateUnconjugated
- Protein IDP13232
- Protein NameInterleukin-7
- Scientific DescriptionThe protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.[provided by RefSeq, Dec 2010]
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352202