Human Insulin ELISA Kit

Arigo Biolaboratories

Human Insulin ELISA Kit

23

ELISA

1.76 microIU/ml

Cross-reactivity: Porcine Insulin (>100%) Bovine Insulin (>100%) Dog Insulin (82%) Rabbit Insulin (63%) Rat Insulin (0%) Human Proinsulin (0%) Porcine Proinsulin (0%) Bovine Proinsulin (0%)

30, 30, 15 min (RT)

Research Use Only

After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5 region and with the IGF2 gene at the 3 region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]

2°C to 8°C

41116133