Human ITGB3BP protein, His tag

GeneTex

Human ITGB3BP protein, His tag

9

Research Use Only

0.5 mg/ml

Unconjugated

ITGB3BP

integrin subunit beta 3 binding protein

CENP-R, CENPR, HSU37139, NRIF3, TAP20, centromere protein R, beta 3 endonexin, beta3-endonexin, integrin beta 3 binding protein (beta3-endonexin), integrin beta-3-binding protein, nuclear receptor-interacting factor 3

Centromere protein R

This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]

-20°C or -80°C,2°C to 8°C

41116100

Human