Human Kremen-1 Protein (KRE-HM201)

KACTUS

Human Kremen-1 Protein (KRE-HM201)

9

Research Use Only

>95%

KREMEN1 (KRM1) has been identified as a functional receptor for Coxsackievirus A10 (CV-A10), a causative agent of hand-foot-and-mouth disease (HFMD), which poses a great threat to infants globally. KRM1 selectively binds to the mature viral particle above the canyon of the viral protein 1 (VP1) subunit and contacts across two adjacent asymmetry units. The key residues for receptor binding are conserved among most KRM1-dependent enteroviruses, suggesting a uniform mechanism for receptor binding.

-20°C or -80°C,-80°C

12352202