Human Lambda Light Chain(ICO-106), CF405S conjugate, 0.1mg/mL [26628-22-8]

Biotium

Human Lambda Light Chain(ICO-106), CF405S conjugate, 0.1mg/mL

9

Research Use Only

Monoclonal

ICO-106

0.1 mg/ml

Other Conjugate

IGL

immunoglobulin lambda locus

ig lambda-6 chain C region; IGL@; IGLC6; immunoglobulin lambda gene cluster

Mouse

IgG1

Immunoglobulin lambda constant 1

This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

2°C to 8°C

12352203