Human Langerin / CD207 ELISA Kit

Arigo Biolaboratories

Human Langerin / CD207 ELISA Kit

23

ELISA

156 pg/ml - 10,000 pg/ml

Intra-Assay CV: 5.8%Inter-Assay CV: 7.2%

13 pg/ml

~ 5 hours

Research Use Only

HRP

C-type lectin domain family 4 member K

The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.

2°C to 8°C

41116100

Human