Human LDH-B protein, His tag (active)

GeneTex

Human LDH-B protein (active)

9

Specific activity is > 300 units/mg, in which one unit will convert 1.0 micromole of pyruvate to L-lactate and beta-NAD per minute at pH 7.5 at 37C.

Research Use Only

1 mg/ml

Unconjugated

Liquid

This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13. [provided by RefSeq, Feb 2016]

-20°C or -80°C,2°C to 8°C

12352204