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Human LIF R, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Human LIF R, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Human LIF R, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

Human LIF R / CD118 Protein, Fc Tag

Research Use Only
LIR-H4252
ACRObiosystems
Product group Molecular Biology
Price on request
Packing Size
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Overview

  • Supplier
    ACRObiosystems
  • Product Name
    Human LIF R / CD118 Protein, Fc Tag
  • Delivery Days Customer
    4
  • Category Supplier
    Bio-Markers & CD Antigens
  • Certification
    Research Use Only
  • Scientific Description
    Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 115.5 kDa. The protein migrates as 140-190 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. Description: Leukemia inhibitory factor receptor is also known as LIFR; CD118; FLJ98106; FLJ99923; LIF-R; SJS2; STWS; SWS, is the receptor for leukemia inhibitory factor (LIF). The leukemia inhibitory factor is a polyfunctional cytokine that affects the differentiation, survival, and proliferation of a wide variety of cells in the adult and the embryo. LIF action appears to be mediated through a high-affinity receptor complex composed of a low-affinity LIF binding chain (LIF receptor) and a high-affinity converter subunit, gp130. Both LIFR and gp130 are members of a family of cytokine receptors that includes components of the receptors for the majority of hematopoietic cytokines and for cytokines that affect other systems, including the ciliary neurotrophic factor, growth hormone and prolactin Defects in LIFR are the cause of Stueve-Wiedemann syndrome (SWS), a severe autosomal recessive condition and belongs to the group of the bent-bone dysplasias.
  • Shelf life instruction
    ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
  • Storage Instruction
    -20℃
  • UNSPSC
    41116133