Human Lymphotoxin Alpha / TNF beta recombinant protein (Active) (His-tagged, N-ter)

Arigo Biolaboratories

Human Lymphotoxin Alpha / TNF beta recombinant protein (Active) (His-tagged, N-ter)

23

Other Application

Research Use Only

>98%

LTA

lymphotoxin alpha

LT, TNFB, TNFSF1, TNLG1E, lymphotoxin-alpha, LT-alpha, TNF superfamily, member 1, TNF-beta, tumor necrosis factor beta, tumor necrosis factor ligand 1E, tumor necrosis factor ligand superfamily member 1

Lymphotoxin-alpha

The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkins lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene.

-20°C

41116120

Human