Human MICA ELISA Kit

Arigo Biolaboratories

Human MICA ELISA Kit

23

ELISA

123 pg/ml

Recognizes both natural and recombinant Human MICA. No cross reactivity with IL-7, IL-12p40, IL-2R, Trail, CD31, IL-13Ralpha2, IL-5, gp130, TNFalpha.

~ 4 hours

Research Use Only

This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2014]

2°C to 8°C

41116133