ARG80167 Human CCL3 / MIP1 alpha ELISA Kit results of a typical standard run with optical density reading at 450 nm.
ARG80167 Human CCL3 / MIP1 alpha ELISA Kit results of a typical standard run with optical density reading at 450 nm.
Human MIP1 alpha / CCL3 ELISA Kit
ARG80167
Product group Assays
Overview
- SupplierArigo Biolaboratories
- Product NameHuman MIP1 alpha / CCL3 ELISA Kit
- Delivery Days Customer23
- ApplicationsELISA
- Assay PrecisionCV:
- Assay Sensitivity15.6 pg/ml
- Assay SpecificityNo significant cross-reactivity or interference with Human MIP-1beta,MIP-1delta,MIP-3alpha,MIP-3beta
- Assay Time4 hours
- CertificationResearch Use Only
- Scientific DescriptionMIP1 alpha belongs to the chemokine beta family. In vitro MIP1 alpha stimulates H2O2 production in human neutrophils. MIP1 alpha and MIP1 beta, two closely related but distinct proteins, were originally co-purified from medium conditioned by a LPS-stimulated murine macrophage cell line. Mature mouse MIP1 alpha shares approximately 77% and 70% amino acid identity with human MIP1 alpha and mouse MIP1 beta, respectively. MIP1 proteins are expressed primarily in T cells, B cells, and monocytes after antigen or mitogen stimulation. Has adhesive effects on lymphocytes. MIP1 alpha can inhibit the proliferation of hematopoietic stem cells in vitro as well as in vivo. A signal transducing receptor, designated the C-C chemokine receptor 1 (C-C CKR-1) with seven transmembrane domains that bind MIP1 alpha, MIP1 beta, MCP1 and RANTES with varying affinities, has been isolated.
- Storage Instruction2°C to 8°C
- UNSPSC41116133