Human MMP7 (active) ELISA Kit

Arigo Biolaboratories

Human MMP7 (active) ELISA Kit

23

ELISA

Intra-Assay CV: 8.9%; Inter-Assay CV: 7.6%

0.102 ng/ml

No specific signal was detected when using pro-MMP7 recombinant protein (20 ng/ml)

~ 4 hours

Research Use Only

MMP7 is a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes on chromosome 11. This gene exhibits elevated expression levels in multiple human cancers. [provided by RefSeq, Jan 2016]

2°C to 8°C

41116133