Human MMP7 Assay Kit

Arigo Biolaboratories

Human MMP7 Assay Kit

23

Functional Assay

4 - 16000 pg/ml

30 pg/ml for 3 hours incubation4 pg/ml for 25 hours incubation

Measures endogenous active MMP7 (naturally occurring) or total active MMP7 (following activation with APMA).

Overnight

Research Use Only

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]

-20°C

41116133