Human NECTIN4 / PVRL4 ELISA Kit

Arigo Biolaboratories

Human NECTIN4 / PVRL4 ELISA Kit

23

ELISA

Intra-Assay CV: 5.5% Inter-Assay CV: 6.1%

15.6 pg/ml

There is no detectable cross-reactivity with other relevant proteins.

~ 5 hours

Research Use Only

This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.[provided by RefSeq, Jan 2011]

2°C to 8°C

41116133