Human Noggin Protein (NOG-HM001)
NOG-HM001
Protein IDQ13253
Product group Proteins / Signaling Molecules
Overview
- SupplierKACTUS
- Product NameHuman Noggin Protein (NOG-HM001)
- Delivery Days Customer9
- CertificationResearch Use Only
- Estimated Purity>95%
- Protein IDQ13253
- Protein NameNoggin
- Scientific DescriptionNoggin is an antagonist of bone morphogenetic proteins (BMP), being indispensable for certain developmental events.Noggin expression positively correlated with EGFR expression in both GC cell line models and The Cancer Genome Atlas human GC cohort. Targeting EGFR and its downstream pathways diminished cell proliferation which was promoted by Noggin. Noggin promotes the proliferation of GC cells by upregulating EGFR and enhancing a vicious circle formed by beta-catenin, EGFR, ERK and Akt.
- Storage Instruction-20°C or -80°C,-80°C
- UNSPSC12352202