Human NOTCH3 ELISA Kit

Arigo Biolaboratories

Human NOTCH3 ELISA Kit

23

ELISA

Intra-Assay CV: < 10%Inter-Assay CV: < 10%

30 pg/ml

4 hours

Research Use Only

HRP

Neurogenic locus notch homolog protein 3

This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq, Jul 2008]

-20°C,2°C to 8°C

41116100

Human