Human NUDT5 ELISA Kit

Arigo Biolaboratories

Human NUDT5 ELISA Kit

23

ELISA

Intra-Assay CV: < 10%Inter-Assay CV: < 10%

50 pg/ml

4 hours

Research Use Only

HRP

ADP-sugar pyrophosphatase

This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates, including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues, resulting in the inhibition of ATP-activated potassium channels. 8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA. Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors.

-20°C,2°C to 8°C

41116100

Human