3 microg of GTX67102-pro Human PAI-1 protein (active) by SDS-PAGE under reducing condition and visualized by coomassie blue stain
3 microg of GTX67102-pro Human PAI-1 protein (active) by SDS-PAGE under reducing condition and visualized by coomassie blue stain
Human PAI-1 protein, His tag (active)
GTX67102-PRO
ApplicationsFunctional Assay
Product group Proteins / Signaling Molecules
Protein IDP05121
Overview
- SupplierGeneTex
- Product NameHuman PAI-1 protein (active)
- Delivery Days Customer9
- Application Supplier NoteThe IC50 for this effect is less than 3 nM, Measured by its ability to inhibit uPA cleavage of the substrate Z-GGR-AMC.
- ApplicationsFunctional Assay
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Protein IDP05121
- Protein NamePlasminogen activator inhibitor 1
- Scientific DescriptionThis gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352202