3microg Human PPM1F protein (GTX68086-pro) by SDS-PAGE under reducing condition and visualized by coomassie blue stain.
3microg Human PPM1F protein (GTX68086-pro) by SDS-PAGE under reducing condition and visualized by coomassie blue stain.
Human PPM1F protein, His tag
GTX68086-PRO
Product group Molecular Biology
Overview
- SupplierGeneTex
- Product NameHuman PPM1F protein
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Protein IDP49593
- Protein NameProtein phosphatase 1F
- Scientific DescriptionThe protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined. [provided by RefSeq, Jul 2008]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352204