Human PROCR, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Human PROCR / EPCR / CD201 Protein, Fc Tag
PRR-H5254
Overview
- SupplierACRObiosystems
- Product NameHuman PROCR / EPCR / CD201 Protein, Fc Tag
- Delivery Days Customer4
- Category SupplierBio-Markers & CD Antigens
- CertificationResearch Use Only
- Estimated Purity95%
- FormatPowder
- Scientific DescriptionCharacteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 48.6 kDa. The protein migrates as 60-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. Description: Endothelial protein C receptor (PROCR) is also known as Activated protein C receptor (APC receptor), Endothelial cell protein C receptor, CD antigen CD201. PROCR / EPCR / CD201 is a N-glycosylated protein, with a soluble form exists. PROCR is probably released by a metalloprotease. PROCR seems to have the same activity as the membrane-bound form. PROCR / EPCR / CD201 is expressed strongly in the endothelial cells of arteries and veins in heart and lung. PROCR binds activated protein C and enhances protein C activation by the thrombin - thrombomodulin complex. PROCR plays a role in the protein C pathway controlling blood coagulation.
- Shelf life instruction● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
- SourceHuman PROCR, Fc Tag (PRR-H5254) is expressed from human 293 cells (HEK293). It contains AA Ser 18 - Thr 209 (Accession # AAH14451).
- ReactivityHuman
- Reactivity SupplierHuman
- Reactivity Supplier NoteC-Fc. HEK293. Ser 18 - Thr 209
- Storage Instruction-20℃
- UNSPSC41116133