Human Purine nucleoside phosphorylase protein, His tag (active)

GeneTex

Human Purine nucleoside phosphorylase protein (active)

9

Specific activity is > 120 units/mg, and is defined as the amount of enzyme that phosphorolysis of 1.0 micromole of inosine with inorganic phosphate per minute at pH 7.5 at 25C.

Research Use Only

1 mg/ml

Unconjugated

Liquid

This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2. [provided by RefSeq, Jul 2008]

-20°C or -80°C,2°C to 8°C

12352204