Human QPRT protein

GeneTex

Human QPRT protein

9

Research Use Only

Unconjugated

This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimers disease, and Huntingtons disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

2°C to 8°C,-20°C or -80°C

41116133