
3microg Human RASSF1 protein (GTX68233-pro) by SDS-PAGE under reducing condition and visualized by coomassie blue stain.
Human RASSF1 protein, His tag
GTX68233-PRO
Overview
- SupplierGeneTex
- Product NameHuman RASSF1 protein
- Delivery Days Customer9
- Concentration1 mg/ml
- FormulationLiquid
- Protein IDQ9NS23
- Protein NameRas association domain-containing protein 1
- Scientific DescriptionThis gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, May 2011]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352202