Human recombinant 4-1BBL (4-1BB ligand) protein, AF

Boster Bio

Human recombinant 4-1BBL (4-1BB ligand) protein, AF

9

Other Application

Research Use Only

>95%

Tumor necrosis factor ligand superfamily member 9

4-1BB ligand (4-1BBL) is a type II transmembrane protein that is part of the tumor necrosis factor (TNF) ligand family. As an inducible co-stimulatory molecule, it presents on several antigen presenting cell (APC) types, including B cells, macrophages and DCs. The interactions between 4-1BB and 4-1BBL trigger pleiotropic effects on the immune response including antigen presenting process, proliferation of CD4 and CD8 positive T-cells, as well as cytokine secretion from T-cells through NFkappaB, c-Jun, and p38 downstream signal pathways activation. Therefore, 4-1BB and 4-1BBL are recently used for the immunotherapy of cancer.

E.coli

-20°C,-20°C or -80°C,2°C to 8°C

12352202