Bio-Connect

Human RGMa Protein (RGM-HM401)

RGM-HM401
KACTUS
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    KACTUS
  • Product Name
    Human RGMa Protein (RGM-HM401)
  • Delivery Days Customer
    9
  • Estimated Purity
    >95%
  • Formulation
    Lyophilized
  • Scientific Description
    Repulsive guidance molecule (RGM) is a glycosylphosphatidylinositol (GPI)-anchored glycoprotein that has diverse functions in the developing and pathological central nervous system (CNS). The binding of RGM to its receptor neogenin regulates axon guidance, neuronal differentiation, and survival during the development of the CNS. RGMa induces T cell activation in experimental autoimmune encephalomyelitis (EAE), which is the animal model of multiple sclerosis (MS). RGM is expressed in pathogenic Th17 cells and induces neurodegeneration by binding to neogenin.
  • Storage Instruction
    -20°C or -80°C,-80°C
  • UNSPSC
    12352202