Human RGMa Protein (RGM-HM401)
RGM-HM401
Product group Proteins / Signaling Molecules
Overview
- SupplierKACTUS
- Product NameHuman RGMa Protein (RGM-HM401)
- Delivery Days Customer9
- Estimated Purity>95%
- FormulationLyophilized
- Scientific DescriptionRepulsive guidance molecule (RGM) is a glycosylphosphatidylinositol (GPI)-anchored glycoprotein that has diverse functions in the developing and pathological central nervous system (CNS). The binding of RGM to its receptor neogenin regulates axon guidance, neuronal differentiation, and survival during the development of the CNS. RGMa induces T cell activation in experimental autoimmune encephalomyelitis (EAE), which is the animal model of multiple sclerosis (MS). RGM is expressed in pathogenic Th17 cells and induces neurodegeneration by binding to neogenin.
- Storage Instruction-20°C or -80°C,-80°C
- UNSPSC12352202