Human RNF34 protein, His tag

GeneTex

Human RNF34 protein, His tag

9

Research Use Only

1 mg/ml

Unconjugated

RNF34

ring finger protein 34

CARP-1, CARP1, RFI, RIF, RIFF, hRFI, E3 ubiquitin-protein ligase RNF34, FYVE-RING finger protein MOMO, RING finger protein RIFF, RING-type E3 ubiquitin transferase RNF34, caspase regulator CARP1, caspases-8 and -10-associated RING finger protein 1, human RING finger homologous to inhibitor of apoptosis protein, ring finger protein 34, E3 ubiquitin protein ligase

E3 ubiquitin-protein ligase RNF34

The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. This protein also targets p53 and phospho-p53 for degradation. Alternatively splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2012]

-20°C or -80°C,2°C to 8°C

41116100

Human