
3microg Human RNF34 protein (GTX68756-pro) by SDS-PAGE under reducing condition and visualized by coomassie blue stain.
Human RNF34 protein, His tag
GTX68756-PRO
Overview
- SupplierGeneTex
- Product NameHuman RNF34 protein
- Delivery Days Customer9
- Concentration1 mg/ml
- FormulationLiquid
- Protein IDQ969K3
- Protein NameE3 ubiquitin-protein ligase RNF34
- Scientific DescriptionThe protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. This protein also targets p53 and phospho-p53 for degradation. Alternatively splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2012]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352202