Human RNF43 Protein (RNF-HM143)

KACTUS

Human RNF43 Protein (RNF-HM143)

9

>95%

Lyophilized

RNF43 (E3 ubiquitin-protein ligase RNF43 or RING-type E3 ubiquitin transferase RNF43) functions as a tumor suppressor, by exerting a predominant negative feedback mechanism in the Wnt/beta-catenin signaling pathway. RNF43 inhibits Wnt/beta-catenin signaling by ubiquitinating Frizzled receptor and targeting it to the lysosomal pathway for degradation.

-20°C or -80°C,-80°C

12352202