Human RUNX1/RUNX2/RUNX3 Ready-To-Use IHC Kit

Bioss

Human RUNX1/RUNX2/RUNX3 Ready-To-Use IHC Kit

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ImmunoHistoChemistry

Research Use Only

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are welldocumented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.

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