Human SEMA4B Protein (SEM-HM14B)
SEM-HM14B
Protein IDQ9NPR2
Product group Proteins / Signaling Molecules
Overview
- SupplierKACTUS
- Product NameHuman SEMA4B Protein (SEM-HM14B)
- Delivery Days Customer9
- Estimated Purity>95%
- Protein IDQ9NPR2
- Protein NameSemaphorin-4B
- Scientific DescriptionSemaphorin 4B (SEMA4B) inhibits the invasion of non-small cell lung cancer (NSCLC) through PI3K-dependent suppression of MMP9 activation. SEMA4B may induce FoxO1 nuclear retention through suppressing PI3K/Akt signaling pathway, which subsequently inhibited cell growth through the direct nuclear target of FoxO1, p21. A role of SEMA4B in suppressing NSCLC growth, besides its role in inhibiting cell metastasis, and highlights SEMA4B as a promising therapeutic target for NSCLC.
- Storage Instruction-20°C or -80°C,-80°C
- UNSPSC12352202