Bio-Connect

Human SIGIRR Protein (SGR-HM201)

SGR-HM201
KACTUS
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    KACTUS
  • Product Name
    Human SIGIRR Protein (SGR-HM201)
  • Delivery Days Customer
    9
  • Estimated Purity
    >95%
  • Scientific Description
    TIR8, also known as single Ig IL-1-related receptor, is a member of the IL-1 receptor/Toll-like receptor (TLR) superfamily, which acts as an intracellular decoy for components of the signaling pathway. Structurally, it is characterized by a single extracellular Ig domain, an intracellular TIR domain and 95-aa cytoplasmic tail. Recently, TIR8 was shown to inhibit NF-B activation by members of the IL-1/TLR family. The inhibitory activity of TIR8 was associated with trapping of TRAF6 and IRAK1.
  • Storage Instruction
    -20°C or -80°C,-80°C
  • UNSPSC
    12352202