Human Siglec 5 + Siglec 14 ELISA kit

Arigo Biolaboratories

Human Siglec 5 + Siglec 14 ELISA kit

23

ELISA

Intra-Assay CV: less than 10%Inter-Assay CV: less than 10%

23.5 pg/ml

~ 4 hours

Research Use Only

HRP

Sialic acid-binding Ig-like lectin 5

Siglec 5 encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. [provided by RefSeq, Feb 2012] Siglec 14 predicted to enable sialic acid binding activity. Predicted to be involved in cell adhesion. Predicted to be located in ficolin-1-rich granule membrane and tertiary granule membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]

2°C to 8°C

41116100

Human