Human Siglec-5/CD170 Protein (SIG-HM405)

KACTUS

Human Siglec-5/CD170 Protein (SIG-HM405)

9

Research Use Only

>95%

Sialic acid-binding Ig-like lectin 5

Siglecs (sialic acid binding Ig-like lectins) are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains. Siglec 5 is putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.

-80°C

12352202