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GTX68612-pro Image
Human TDP1 protein
![Research Use Only](static/images/certificates/ruo.jpg)
GTX68612-PRO
Overview
- SupplierGeneTex
- Product NameHuman TDP1 protein
- Delivery Days Customer10
- CertificationResearch Use Only
- Concentration0.25 mg/ml
- Protein IDQ9NUW8
- Protein NameTyrosyl-DNA phosphodiesterase 1
- Scientific DescriptionThe protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). [provided by RefSeq, Aug 2016]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352202