Bio-Connect
Functional ELISA analysis of GTX00420-pro Human Thymidylate synthase protein which can bind immobilized AST protein.
Functional ELISA analysis of GTX00420-pro Human Thymidylate synthase protein which can bind immobilized AST protein.
Functional ELISA analysis of GTX00420-pro Human Thymidylate synthase protein which can bind immobilized AST protein.

Human Thymidylate synthase protein (active)

Research Use Only
GTX00420-PRO
GeneTex
Product group Molecular Biology
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    Human Thymidylate synthase protein (active)
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Conjugate
    Unconjugated
  • Scientific Description
    Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using, 10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occurring antisense transcript, mitochondrial enolase superfamily member 1 (GeneID:55556), vary inversely when cell-growth progresses from late-log to plateau phase. Polymorphisms in this gene may be associated with etiology of neoplasia, including breast cancer, and response to chemotherapy. [provided by RefSeq, Aug 2017]
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    41116133