Human Tpo / Thrombopoietin recombinant protein (Active) (His-tagged, N-ter)
ARG70139
ApplicationsOther Application
Product group Proteins / Signaling Molecules
Protein IDP40225
Overview
- SupplierArigo Biolaboratories
- Product NameHuman Tpo / Thrombopoietin recombinant protein (Active) (His-tagged, N-ter)
- Delivery Days Customer23
- ApplicationsOther Application
- CertificationResearch Use Only
- Estimated Purity>95%
- Protein IDP40225
- Protein NameThrombopoietin
- Scientific DescriptionMegakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5 UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent. [provided by RefSeq, Feb 2014]
- Storage Instruction-20°C
- UNSPSC12352202