Human TSLP recombinant protein (His-tagged, C-ter)

Arigo Biolaboratories

Human TSLP recombinant protein (His-tagged, C-ter)

23

Other Application

Research Use Only

>98%

TSLP

thymic stromal lymphopoietin

thymic stromal lymphopoietin, thymic stroma-derived lymphopoietin

Thymic stromal lymphopoietin

This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]

-20°C

41116120

Human