Human VEGFA / VEGF Protein (Recombinant) (aa27-141)
LS-G136183
Product group Proteins / Signaling Molecules
Overview
- SupplierLifeSpan BioSciences
- Product NameHuman VEGFA / VEGF Protein (Recombinant) (aa27-141)
- Delivery Days Customer14
- CertificationResearch Use Only
- Concentration0.5 mg/ml
- Estimated Purity...
- Scientific DescriptionRecombinant Human VEGF-AVascular endothelial growth factor alpha forms a homodimer and is a potent stimulator of angiogenesis of both normal and cancerous cells. It acts as a regulator of vasculogenesis, angiogenesis and endothelial cell growth. VEGF-A is secreted by many different cell types such as endothelial cells, smooth muscle cells, neutrophils, platelets, macrophages and 60% of all tumours. The sequence of this recombinant protein product is aa 27-141 + CDKPRR but deficient from aa 142-226, and it is closest to isoform 121. Isoform 121 and 111 lack exons 6 and 7, and for this reason neither of these isoforms bind to the extracellular matrix. This product has been demonstrated for use, in a pharmacokinetic (PK) antigen capture ELISA with the monoclonal antibody drugs ranibizumab and bevacizumab using anti-ranibizumab antibodies for detection.
- UNSPSC12352202