Human/Canine/Porcine Insulin ELISA Kit
ARG82618
Product group Assays
Overview
- SupplierArigo Biolaboratories
- Product NameHuman/Canine/Porcine Insulin ELISA Kit
- Delivery Days Customer23
- ApplicationsELISA
- Assay PrecisionIntra-Assay CV: 4.5%Inter-Assay CV: 4.2%
- Assay Sensitivity3.9 pmol/L
- Assay SpecificityThis kit could assay both natural and recombinant Human/Canine/Porcine Insulin.No significant cross-reactivity or interference was observed in the following samples:Human: C-peptide, IGF1, IGF2, IL2, IL4, IL6, IL8, IL10, IL12, IL18, IL22, Insulin R, MCP1,
- Assay Time~ 2.5 hours
- CertificationResearch Use Only
- Scientific DescriptionAfter removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5 region and with the IGF2 gene at the 3 region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
- Storage Instruction2°C to 8°C
- UNSPSC41116133