Human/Mouse HIF-1 alpha ELISA Kit

Arigo Biolaboratories

Human/Mouse HIF-1 alpha ELISA Kit

23

ELISA

125 - 8000 pg/ml

100 pg/ml

No cross-reaction with other related substances detected.

4 hours

Research Use Only

This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011]

2°C to 8°C

41116133