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ProductsBack/(+/-)-Huperzine A [120786-18-7]

(+/-)-Huperzine A [120786-18-7]

Research Use Only
HY-17388
MedChem Express
CAS Number120786-18-7
DownloadMSDS
Product group Chemicals
Estimated Purity98.73
Molecular Weight242.322
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Overview

  • Supplier
    MedChem Express
  • Product Name
    (+/-)-Huperzine A [120786-18-7]
  • Delivery Days Customer
    10
  • CAS Number
    120786-18-7
  • Certification
    Research Use Only
  • Estimated Purity
    98.73
  • Molecular Formula
    C15H18N2O
  • Molecular Weight
    242.322
  • Scientific Description
    (+/-)-Huperzine A, an active Lycopodium alkaloid extracted from traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the treatment of Alzheimers disease (AD). IC50 value: Target: AChE (+/-)-Huperzine A exhibited protective effects against d-gal-induced hepatotoxicity and inflamm-aging by inhibiting AChE activity and via the activation of the cholinergic anti-inflammatory pathway. The (+/-)-Huperzine A mechanism might be involved in the inhibition of DAMPs-mediated NF-kappaB nuclear localization and activation. (+/-)-Huperzine A is a potential therapeutic agent for Alzheimers disease.
  • SMILES
    O=C1C=CC(C(/C2=C/C)(N)CC(C)=CC2C3)=C3N1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200