
Western blot using GeneTexs affinity purified anti-Hus1B antibody shows detection of a 36kDa band corresponding to Hus1B in a HeLa cell lysate (arrowhead). The staining pattern in 293 cells is less clear, showing a predominant band at 39 kDa.
HUS1B antibody
GTX48745
ApplicationsImmunoPrecipitation, Western Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetHUS1B
Overview
- SupplierGeneTex
- Product NameHUS1B antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:5000. IP: 1:100. ELISA: 1:20000-1:100000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoPrecipitation, Western Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.75 mg/ml
- ConjugateUnconjugated
- Gene ID135458
- Target nameHUS1B
- Target descriptionHUS1 checkpoint clamp component B
- Target synonymscheckpoint protein HUS1B; hHUS1B; HUS1 checkpoint homolog b
- HostRabbit
- IsotypeIgG
- Protein IDQ8NHY5
- Protein NameCheckpoint protein HUS1B
- Scientific DescriptionThe protein encoded by the Hus1B gene is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the checkpoint protein RAD1 but not with RAD9. Over expression of this protein has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to HUS1. Hus1B is expressed strongly in testis, less in spleen, thymus, prostate, colon and leukocytes.
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203