HXR9 (hydrochloride)

MedChem Express

HXR9 (hydrochloride)

10

Research Use Only

99.20

HXR9 hydrochloride is a cell-permeable peptide and a competitive antagonist of HOX/PBX interaction . HXR9 hydrochloride antagonizes the interaction between HOX and a second transcrip-tion factor (PBX), which binds to HOX proteins in paralogue groups1 to 8. HXR9 hydrochloride selectively decreases cell proliferation and promotes apoptosis in cells with a high level of expression of the HOXA/PBX3 genes, such as MLL -rearranged leukemic cells [1] [2] [3] .

-20°C,-80°C

12352202