Bio-Connect

HYAL2 Polyclonal Antibody

RD75902A
Reddot Biotech
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetHYAL2
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    HYAL2 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.6 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID8692
  • Target name
    HYAL2
  • Target description
    hyaluronidase 2
  • Target synonyms
    hyal-2; hyaluronidase-2; hyaluronoglucosaminidase 2; LUCA2; lung carcinoma protein 2; lysosomal hyaluronidase; PH20 homolog; PH-20 homolog
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5 UTR.
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203