Hycanthone [3105-97-3]

MedChem Express

Hycanthone [3105-97-3]

10

3105-97-3

Research Use Only

99.97

C20H24N2O2S

356.48

Hycanthone is a thioxanthenone DNA intercalator and inhibits RNA synthesis as well as the DNA topoisomerases I and II. Hycanthone inhibits nucleic acid biosynthesis and inhibits apurinic endonuclease-1 (APE1) by direct protein binding with a KD of 10 nM. Hycanthone is a bioactive metabolite of Lucanthone (HY-B2098) and has anti-schistosomal agent[1].

O=C1C2=C(SC3=C1C=CC=C3)C(CO)=CC=C2NCCN(CC)CC

-20°C,2°C to 8°C

12352200