Hydrochlorothiazide [58-93-5]

MedChem Express

Hydrochlorothiazide [58-93-5]

10

58-93-5

Research Use Only

99.46

C7H8ClN3O4S2

297.745

Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-beta/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect[1][2][3].

O=S(C1=C(Cl)C=C(C2=C1)NCNS2(=O)=O)(N)=O

-20°C,2°C to 8°C

12352200