Hydroxy-Dynasore

MedChem Express

Hydroxy-Dynasore [1256493-34-1]

9

1256493-34-1

Research Use Only

99.11

C18H14N2O5

338.31

Hydroxy Dynasore (Dyngo-4a), a structural mimetic analog of Dynasore (HY-15304), is an improved, less cytotoxic and versatile dynamin inhibitor with IC 50 values of 0.38 microM and 2.3 microM for brain recombinant dynamin I and recombinant mouse dynamin II, respectively. Hydroxy Dynasore inhibits dynamin-dependent transferrin endocytosis with an IC 50 of 5.7 microM.

OC1=CC2=CC=CC=C2C=C1C(N/N=C/C3=C(O)C=C(O)C(O)=C3)=O

-20°C,2°C to 8°C

12352200