Hymeglusin [29066-42-0]

MedChem Express

Hymeglusin [29066-42-0]

10

29066-42-0

Research Use Only

99.30

C18H28O5

324.41

Hymeglusin, as a fungal beta-lactone antibiotic, is a HMG-CoA synthase inhibitor (IC50 = 0.12 microM). Hymeglusin covalently modifies the active Cys129 residue of the enzyme[2][3].

O=C(O)/C=C(C)/C=C(C)/C[C@H](C)CCCC[C@H]([C@H]1CO)OC1=O

-20°C

12352200