Hypaconitine

MedChem Express

Hypaconitine [6900-87-4]

10

6900-87-4

Research Use Only

99.49

C33H45NO10

615.71

Hypaconitine inhibits the KCNH2 current with an IC50 of 8.1 nM, and exhibits cardiotoxicity. Hypaconitine inhibits TGF-beta1-induced epithelial-mesenchymal transition (EMT) in A549 cell through the inhibition of NF-kappaB nuclear translocation. Hypaconitine acts as the neuromuscular blocker. Hypaconitine is orally active[1][2][3][4].

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-20°C,2°C to 8°C

12352200