HYS-072

MedChem Express

HYS-072

5

Research Use Only

C27H26N2O5

458.51

HYS-072 is an orally active derivative of chrysin (HY-14589) with antitumor activity. HYS-072 induces apoptosis and autophagy by inhibiting the PI3K/AKT/mTOR signaling pathway and suppresses tumor growth in vivo in xenograft models by modulating autophagy-related pathways. HYS-072 can be used in the research of triple-negative breast cancer[1].

CC1=CC=C(NC(NCCCCOC2=CC(O)=C3C(OC(C4=CC=CC=C4)=CC3=O)=C2)=O)C=C1

12352200